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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPN9
All Species:
39.09
Human Site:
Y160
Identified Species:
78.18
UniProt:
P43378
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43378
NP_002824.1
593
68020
Y160
Y
D
M
C
G
S
N
Y
A
N
F
E
L
D
L
Chimpanzee
Pan troglodytes
XP_001144390
596
67599
Y160
Y
D
M
C
G
S
N
Y
A
N
F
E
L
D
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_854411
607
69728
Y174
Y
D
M
C
G
S
N
Y
T
N
F
E
L
D
L
Cat
Felis silvestris
Mouse
Mus musculus
O35239
593
67952
Y160
Y
D
M
C
G
S
N
Y
A
N
F
E
L
D
L
Rat
Rattus norvegicus
Q641Z2
593
67944
Y160
Y
D
M
C
G
S
N
Y
A
N
F
E
L
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505361
613
70033
Y172
Y
D
M
G
G
S
H
Y
T
N
F
E
L
D
L
Chicken
Gallus gallus
XP_413696
584
66275
Y150
Y
D
M
A
G
S
Q
Y
T
N
F
E
L
D
L
Frog
Xenopus laevis
NP_001081203
694
79518
Y150
Y
D
M
I
N
S
T
Y
G
N
F
D
Y
E
L
Zebra Danio
Brachydanio rerio
XP_001923429
571
65239
Y151
Y
D
M
A
G
S
N
Y
T
N
F
E
L
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727356
797
85738
Y206
Y
D
M
S
G
S
K
Y
S
N
F
D
Y
D
L
Honey Bee
Apis mellifera
XP_394701
660
73346
Y150
Y
D
M
S
D
S
K
Y
Q
N
F
D
Y
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200442
281
32148
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.9
N.A.
92
N.A.
97.3
97.1
N.A.
75.8
74
44.3
67.7
N.A.
35.6
43.4
N.A.
25.8
Protein Similarity:
100
94.6
N.A.
94.4
N.A.
98.6
98.9
N.A.
87.4
84.4
61
81.6
N.A.
49.1
60.6
N.A.
34.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
80
80
53.3
86.6
N.A.
66.6
60
N.A.
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
86.6
80
66.6
86.6
N.A.
80
66.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
0
0
0
0
34
0
0
0
0
0
0
% A
% Cys:
0
0
0
42
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
92
0
0
9
0
0
0
0
0
0
25
0
84
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
67
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
92
0
0
0
0
% F
% Gly:
0
0
0
9
75
0
0
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
67
0
92
% L
% Met:
0
0
92
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
50
0
0
92
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
17
0
92
0
0
9
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
0
34
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
92
0
0
0
0
0
0
92
0
0
0
0
25
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _